Proteomics Just Served Up: Membrane Topology on a Proteome Scale | GenomeWeb

If proteomics could be thought of as a smorgasbord, then the membrane proteome is its fermented Baltic herring — tough to deal with initially, but valuable once you’ve acquired the skill to appreciate it. Membrane proteins are themselves consistently fickle and hard to characterize, yet prized as some of the most therapeutically interesting proteins because of their tendency to serve as gatekeepers to the cytoplasm.

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