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Proteome Systems and the Buck Institute to Study Proteomics of Aging

NEW YORK, Aug. 20 – Proteome Systems and the Buck Institute for Age Research have agreed jointly to study proteins involved in aging using Proteome Systems' proteomics technologies, the company said on Monday.

The groups, which will conduct their studies using mice and worms, plan to identify proteins in the mitochondria of brain cells involved in oxidative stress and aging, Mary Lopez, Proteome Systems' executive vice president of proteomics R&D in the US, told GenomeWeb .

“We’re going to be focusing on mitochondrial proteins, but we won’t be limited to that," Lopez said. "We will be working with mice, mainly mouse brains. And also C. elegans."

Lopez said the partnership with the Buck Institute, based in Novato, Calif., had been under discussion for about a year. She could not disclose financial details.

“As the first freestanding institute devoted to basic research on aging and age-associated diseases, we hope to help shape the future of aging research, and to do this we need to work with groups that have cutting edge technology and creative people to facilitate our research programs,” Dale Bredesen, CEO of the Buck Institute, said in a statement.

In addition to conducting its own proteomics research, Proteome Systems sells 2D gel electrophoresis instrumentation, sample preparation kits, and equipment for mass spectrometry analysis of proteins in partnership with Sigma and Kratos Analytical, a subsidiary of Shimadzu Biotech.

In June, Proteome Systems, which has offices in Sydney, Australia, and Boston, established a collaboration with researchers at the University of Missouri-Columbia to study the proteins involved in resistance to cancer drugs.

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