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Protein Pathways and Merck Collaborate

NEW YORK, April 4 - Protein Pathways said this week that it has started a research collaboration with Merck.


Wyeth will apply the company's pathway prediction technology to its drug discovery efforts.


Protein Pathways, based in Woodland Hills, Calif., predicts and integrates protein interaction networks from various types of data, including DNA sequence data, microarray gene expression data, literature abstracts, and protein interaction data, using proprietary computational methods.


It has constructed a human protein interaction map that includes more than 200,000 predicted interactions.


The company exclusively licenses technology developed by David Eisenberg at the University of California Los Angeles.

The Scan

Purnell Choppin Dies

Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.

Effectiveness May Decline, Data From Israel Suggests

The New York Times reports that new Israeli data suggests a decline in Pfizer-BioNTech SARS-CoV-2 vaccine effectiveness against Delta variant infection, though protection against severe disease remains high.

To See Future Risk

Slate looks into the use of polygenic risk scores in embryo screening.

PLOS Papers on Methicillin-Resistant Staphylococcus, Bone Marrow Smear Sequencing, More

In PLOS this week: genomic analysis of methicillin-resistant Staphylococcus pseudintermedius, archived bone marrow sequencing, and more.