Predicting HLA genotypes using unphased and flanking single-nucleotide polymorphisms in Han Chinese population.
BMC Genomics. 2014 Jan 29;15(1):81. [Epub ahead of print]
Hsieh A, et al.
The authors used Affymetrix and Illumina SNP chip data obtained from Han Chinese samples to build a prediction model of HLA genes that are specific for a Han Chinese population. To optimize their model, they analyzed a number of critical parameters, including flanking-region size, genotyping platform, and imputation.
Residual feed intake of lactating Holstein-Friesian cows predicted from high-density genotypes and phenotyping of growing heifers.
J Dairy Sci. 2014 Jan 25. pii: S0022-0302(14)00057-5. [Epub ahead of print]
Davis S, et al.
The authors used the Illumina Bovine SNP50 BeadChip to predict and test breeding values for residual feed intake in lactating cows from an independent, industry population.
Chromosomal microarray analysis of consecutive individuals with autism spectrum disorders or learning disability presenting for genetic services.
Gene. 2014 Feb 1;535(1):70-8.
Roberts J, et al.
The authors report their experience with the use of chromosomal microarrays in 215 consecutive patients referred with either autism or autism spectrum disorders or developmental delay/learning disability for genetic services at the University of Kansas Medical Center during the past four years diagnostics.
Usefulness of frataxin immunoassays for the diagnosis of Friedreich ataxia.
J Neurol Neurosurg Psychiatry. 2014 Jan 24. [Epub ahead of print]
Deutsch E, et al.
The authors set out to evaluate the performance of frataxin measurements as a diagnostic tool for the autosomal recessive inherited disease using two different immunoassays. They compared a lateral flow immunoassay with a multianalyte Luminex xMAP-based immunoassay, and showed that both assays demonstrate high positive predictive values with low rates of false negatives and false positives.