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In Print: Last Week's Microarray Papers of Note: Jul 9, 2013


Familial haplotyping and embryo analysis for Preimplantation Genetic Diagnosis (PGD) using DNA microarrays: a proof of principle study.
J Assist Reprod Genet. 2013 Jul 6. [Epub ahead of print]
Altarescu G, Zeevi D, Zeligson S, et al.

A PGD cycle was performed for a couple with paternal Charcot Marie Tooth 1A using a classic multiplex nested PCR approach. Mutant embryos from the case were blindly reanalyzed using SNP microarrays. After applying a unique informative allele selection algorithm to the data, the array-based assay reconfirmed the initial diagnosis in all samples.

First report of fingerprinting dried herbal products using a subtractive diversity array.
J Complement Integr Med. 2013 Jul 3;10(1):1-11.
Niu L, Mantri N, Wohlmuth H, et al.

The authors report the successful fingerprinting of seven species: Leonurus sibiricus, Astragalus membranaceus, Coix lachryma-jobi, Magnolia biondii, Abutilon theophrasti, Physalis alkekengi, and Salvia miltiorrhiza from dried tissues using a sequence-independent microarray. They claim their technique provides a new way to produce markers for authenticating dried herbal samples.

Neonatal levels of neurotrophic factors and risk of autism spectrum disorders.
Acta Psychiatr Scand. 2013 Jul;128(1):61-9.
Abdallah M, Mortensen E, Greaves-Lord K, et al.

The authors used Luminex assays to examine levels of three neurotrophic factors — brain derived neurotrophic factor, neurotrophin-4, and transforming growth factor-β — in dried blood spot samples of neonates diagnosed with autism spectrum disorders later in life. Results cautiously indicate decreased NTFs levels during neonatal period in ASD.

The Scan

NFTs for Genome Sharing

Nature News writes that non-fungible tokens could be a way for people to profit from sharing genomic data.

Wastewater Warning System

Time magazine writes that cities and college campuses are monitoring sewage for SARS-CoV-2, an approach officials hope lasts beyond COVID-19.

Networks to Boost Surveillance

Scientific American writes that new organizations and networks aim to improve the ability of developing countries to conduct SARS-CoV-2 genomic surveillance.

Genome Biology Papers on Gastric Cancer Epimutations, BUTTERFLY, GUNC Tool

In Genome Biology this week: recurrent epigenetic mutations in gastric cancer, correction tool for unique molecular identifier-based assays, and more.