Predictions and Changes


It’s a prediction we’ve all heard before: when sequencing got cheap enough, prognosticators said, scientists would abandon their microarrays entirely. We’d all be using chip scanners for doorstops.

In our cover story, we follow up on that prediction to see if arrays really are spiraling into obsolescence. It turns out that while next-gen sequencing has taken away — apps like ChIP appear set for a sequencer-only world — it has also given, creating demand for arrays in new sample prep and validation techniques.

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Gene drives might run into biological resistance, the Economist reports.

Forensic experts exhumed painter Salvador Dalí's body to collect DNA for a paternity test, CBS News reports.

Yale Environment 360 writes that synthetic and conservation biologists aren't always on the same wavelength, but they are trying to reach an understanding.

In Science this week: full CRISPR locus integration complex structure, and more.