Skip to main content
Premium Trial:

Request an Annual Quote

Precision BioSciences Sues Lonza for Patent Infringement

NEW YORK (GenomeWeb News) – Precision BioSciences said today that it is suing Lonza Group and a number of its affiliates for patent infringement.

The lawsuit, filed in the US District Court for the District of Delaware, alleges that Switzerland-based Lonza's import and sale of its GS Xceed Gene Expression System and CHOK1SV knock-out cell line in the US infringes US Patent No. 8,377,674, which applies to Precision Bio's Directed Nuclease Editor genome editing technology.

According to the patent's abstract, the technology pertains to "[r]ationally designed LAGLIDADG meganucleases and methods of making such meganucleases." The patent also covers methods of using the meganucleases in order to generate recombinant cells and organisms "having a desired DNA sequence inserted into a limited number of loci within the genome" and other methods.

Precision Bio is asking for monetary damages and a permanent injunction preventing Lonza from importing and selling the GS Xceed Gene Expression System and CHOK1SV knock-out cell line in the US.

"Precision prefers to focus its business development efforts in a positive and productive manner," Matthew Kane, CEO of Precision Bio, said in a statement. "However, willful infringement of Precision's proprietary gene editing technology cannot be tolerated. … We cannot allow Lonza to import, market, and sell a product developed using our intellectual property to customers in the United States without a license to do so."

The Research Triangle Park, NC-based firm is embroiled in several patent infringement lawsuits with Paris-based Cellectis, and last month claimed victory in one of those cases.

The Scan

Cell Atlas of Human Lung Development Gives View of Developing Airway

Researchers have generated a cell atlas of human lung development, which they report in Cell.

Study Finds Costs of Genome Sequencing May Limit Utility in Routine Care

Researchers report in the European Journal of Human Genetics that genome sequencing for rare disease diagnoses currently has similar benefits as less expensive exome analysis.

Study Suggests Nursing Mother's Diet Can Impact Offspring's Gut Microbiome

A new Cell Host and Microbe paper finds that mice whose mothers were fed a low-fiber diet during nursing experience lasting microbiota dysbiosis and increased obesity.

Study Links Genetic Risk for ADHD With Alzheimer's Disease

A higher polygenic risk score for attention-deficit/hyperactivity disorder is also linked to cognitive decline and Alzheimer's disease, a new study in Molecular Psychiatry finds.