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Physiomics to Use Simulation Software to Select Targets for Cronos

NEW YORK, Nov. 24 (GenomeWeb News) - Physiomics will select drug targets for Cronos Therapeutics using its cell cycle simulation software, the UK-based companies said yesterday.


Physiomics, located in Oxford, will use its mammalian cell cycle model, which is linked to PK-Sim drug delivery software from Bayer Technology Services in Germany, to select the best targets for Cronos' GeneICE gene silencing technology.


GeneICE prevents transcription by using cellular gene repressor complexes that interact with the target gene and modify its chromatin structure.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.