NEW YORK, April 4 (GenomeWeb News) - Perlegen Sciences has won a two-year biodefense partnership grant from the National Institute of Allergy and Infectious Diseases to genotype the plague bacterium and a related species, the company said today.
In collaboration with scientists at Lawrence Berkeley National Laboratory, Perlegen will use its oligo array technology to genotype the genomes of approximately 150 strains of Yersinia pestis, which causes the plague, and Yersinia pseudotuberculosis, a closely related bacterium.
The aim is to discover a genome-wide set of SNPs that will help to distinguish different strains and understand their biology. Perlegen plans to make the SNPs publicly available through dbSNP and othr websites.
The amount of the grant was not immediately available from Perlegen, but NIH databases list a two-year grant to Perlegen in 2005 entitled "Signature SNPs to Distinguish Yersinia Pestis Strains" with an award of $1.66 million in fiscal year 2005.