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Perlegen to Identify Heart Attack Gene Variants for AstraZeneca

NEW YORK, Jan. 9  (GenomeWeb News) - Perlegen Sciences and AstraZeneca will collaborate in a study that aims to find gene variants that increase the risk for heart attack, Perlegen said today.


Perlegen, of Mountain View, Calif., plans to genotype for AstraZeneca over one thousand samples to identify SNPs in genes and other genetic loci that are associated with heart attack.


The agreement follows on the heels of two research collaborations with Pfizer, in the areas of Major Depression Disorder and Metabolic Syndrome, that Perlegen announced earlier this week.


The Scan

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.

Team Presents Cattle Genotype-Tissue Expression Atlas

Using RNA sequences representing thousands of cattle samples, researchers looked at relationships between cattle genotype and tissue expression in Nature Genetics.

Researchers Map Recombination in Khoe-San Population

With whole-genome sequences for dozens of individuals from the Nama population, researchers saw in Genome Biology fine-scale recombination patterns that clustered outside of other populations.

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.