The partners plan to genotype SNPs in patients and controls and validate the results in a separate study. PNDRC will also examine how genetic variations correlate with changes in gene expression.
DNA samples will come from projects that participated in the National Institute of Mental Health Bipolar Disorder Genetics Initiative, and controls from the NIMH Molecular Genetics of Schizophrenia Initiative.
PNDRC is a collaboration between several academic groups, including the University of Michigan,