NEW YORK (GenomeWeb News) – An international team of researchers led by the University of Pennsylvania's academic medical center, Penn Medicine, will use a $6 million grant from a French non-profit foundation to study genes that are involved in atherosclerotic cardiovascular disease, the university said today.
Scientists at Penn Medicine's Institute for Translational Medicine and Therapeutics will use the grant from the Fondation Leducq in Paris to look closely at the molecular mechanisms underlying genes that have been identified through genome-wide association studies for their potential involvement in coronary heart disease and heart attack.
Funded under the foundation's Transatlantic Networks of Excellence Program, the researchers plan to study six novel genes found by genome-wide association studies to be associated with heart disease in order to assess how they are involved in the processes that underlie cardiovascular disease and whether or not they are viable targets for therapeutic development.
The international research team includes experts in epidemiology, human genetics, molecular and cell biology, and animal physiology. The group includes scientists at Aachen University, Stanford University, Harvard Medical School, Massachusetts General Hospital, the University of Cambridge, the European Molecular Biology Laboratory, Columbia University, Lund University, the University of Western Ontario, the University of Heidelberg, and the University of Sheffield.