Skip to main content
Premium Trial:

Request an Annual Quote

Pattern Recognition Ranking SNP/Genotyping Technology




SNP/genetic variation databases were ranked by converting respondents’ ratings (“not useful/problematic,” “somewhat useful, but flawed,” “useful,” or “very useful”) and normalizing for the number of ratings given each platform. The Mouse SNP database scored the highest with a ranking of 292 (out of a possible 400), indicating that more than 90 percent of the database users who responded to the survey consider it “useful” or “very useful.”


1. Mouse SNP database, hosted by Roche (292)

2. NCBI public dbSNP, hosted by National Center for Biotechnology Information (270)

3. Human Genome Variation database, hosted by Karolinska Institute (257)

4. HAP database, Genaissance Pharmaceuticals (250)

5. The SNP Consortium database, hosted by Cold Spring Harbor Laboratory (238)

6. The Human Genome Mutation Database, hosted by University of Wales, Cardiff (200)



SNP/genotyping platforms were ranked by converting respondents’ ratings (either “poor,” “fair,” “good,” or “excellent”) into a points-based system and normalizing for the number of ratings given each platform. The highest possible score was 400, meaning more than 70 percent of Sequenom MassArray users who responded to the survey rated the platform either “good” or “excellent.”


1. Sequenom MassArray (276)

2. Affymetrix HuSNP probe array (250)

3. Applied Biosystems Assays on Demand (239)

4. Pyrosequencing PSQ system (226)

5. Orchid SNPstream (219)

6. Third Wave Invader Platform (209)

7. Illumina BeadArrays (200)

8. Amersham SNuPe kit (123)




By converting respondents’ ratings of companies involved in SNPs, genotyping, or pharmacogenomics research (“going in the wrong direction,” “of potential interest but not critical now,” and “critically important to my field”) into a points-based system and normalizing for the number of ratings given each platform, the following picture emerges of the value placed on companies’ research. GlaxoSmithKline was highest ranked with a score of 196 (out of 300); slightly more than half of survey repondents rated GSK’s research “of potential interest but not critical now,” and the rest rated its work in SNPs “critically important to my field.”


1. GlaxoSmithKline, Brentford, UK (196)

2. Perlegen Sciences, Mountain View, Calif. (155)

3. Roche, Basel, Switzerland (153)

4. Genaissance Pharmaceuticals, New Haven, Conn. (147)

5. Sequenom, San Diego, Calif. (139)

6. DeCode Genetics, Reykjavik, Iceland (136)

7. DNA Sciences, Fremont, Calif. (129)

8. Third Wave Technologies, Madison, Wis. (113)

9. Amersham Biosciences, Little Chalfont, UK (111)

10. Celera Genomics, Rockville, Md. (100)

11. Variagenics, Sunnyvale, Calif. (96)

12. Incyte, Palo Alto, Calif. (89)

13. Orchid Biosciences, Princeton, NJ (80)


For more information about obtaining a full copy of the report, visit


The Scan

Transcriptomic, Epigenetic Study Appears to Explain Anti-Viral Effects of TB Vaccine

Researchers report in Science Advances on an interferon signature and long-term shifts in monocyte cell DNA methylation in Bacille Calmette-Guérin-vaccinated infant samples.

DNA Storage Method Taps Into Gene Editing Technology

With a dual-plasmid system informed by gene editing, researchers re-wrote DNA sequences in E. coli to store Charles Dickens prose over hundreds of generations, as they recount in Science Advances.

Researchers Model Microbiome Dynamics in Effort to Understand Chronic Human Conditions

Investigators demonstrate in PLOS Computational Biology a computational method for following microbiome dynamics in the absence of longitudinally collected samples.

New Study Highlights Role of Genetics in ADHD

Researchers report in Nature Genetics on differences in genetic architecture between ADHD affecting children versus ADHD that persists into adulthood or is diagnosed in adults.