Pathway Linked to Cocaine-Related Brain Changes in Mice | GenomeWeb

A research team has uncovered a pathway governing the histone modifications that occur following repeated cocaine use in mice — findings that provide clues about cocaine-related changes observed in a brain region implicated in drug use.

The team knew from past studies that cocaine use leads to widespread gene activation, with epigenetic processes contributing to these changes, says lead author Ian Maze, a graduate student in Eric Nestler's Mount Sinai School of Medicine lab.

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The White House has created a list of cuts, including to the NIH, that could be in a budget bill for this year.

The US National Institutes of Health is to allow applicants to cite preprints just as they would any other research paper, ScienceInsider reports.

Two manuscript pages handwritten by Charles Darwin are going on the auction block, according to the Los Angeles Times.

In PNAS this week: tool to track transcriptome-wide binding, evidence of balancing selection on behavior-linked genes, and more.