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ParAllele and U of Iowa Partner on AMD Gene Discovery

NEW YORK, March 29 (GenomeWeb News) - ParAllele Bioscience is collaborating with the University of Iowa to accelerate the discovery of genes associated with age-related macular degeneration, the company said today.

 

The research will be led by Gregory Hageman, a professor at the University of Iowa Carver College of Medicine, and will bring together U of Iowa's Cell Biology and Functional Genomics Laboratory, Department of Opthalmology and Visual Sciences, and Center for Macular Degeneration.

 

Hageman's work is funded by the National Eye Institute at the National Institutes of Health and additional undisclosed corporate entities, ParAllele said.

The Scan

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.

Team Presents Cattle Genotype-Tissue Expression Atlas

Using RNA sequences representing thousands of cattle samples, researchers looked at relationships between cattle genotype and tissue expression in Nature Genetics.

Researchers Map Recombination in Khoe-San Population

With whole-genome sequences for dozens of individuals from the Nama population, researchers saw in Genome Biology fine-scale recombination patterns that clustered outside of other populations.

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.