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Paradigm Wins Third US Patent for Fungicide Technology

NEW YORK, May 15 - Paradigm Genetics has been issued a patent in the United States for "Methods and Materials for the Rapid and High Volume Production of a Gene Knock-Out Library in an Organism."


The patent, No. 6,562,624, covers Paradigm's Transposon-Arrayed Gene Knock-Out technology, which according to the company provides methods "for the rapid and systematic mutation of pathogenic fungi." These methods are designed to enable researchers to identify antifungal and fungicide targets, as well as biosynthetic and degradation pathways, Paradigm said.


To date, Paradigm has won two Notices of Allowance from the US Patent and Trademark Office for fungicide target patent applications. They are: "Methods for the Identification of Inhibitors of 5-Aminolevulinate Synthase as Antibiotics" and "Methods for the Identification of Inhibitors of Threonine Synthase as Antibiotics."

The Scan

And Back

The New York Times reports that missing SARS-CoV-2 genome sequences are back in a different database.

Lacks Family Hires Attorney

A lawyer for the family of Henrietta Lacks plans to seek compensation from pharmaceutical companies that have used her cancer cells in product development, the Baltimore Sun reports.

For the Unknown

The Associated Press reports that family members are calling on the US military to use new DNA analysis techniques to identify unknown sailors and Marines who were on the USS Arizona.

PLOS Papers on Congenital Heart Disease, COVID-19 Infection Host MicroRNAs, Multiple Malformation Mutations

In PLOS this week: new genes linked to congenital heart disease, microRNAs with altered expression in COVID-19, and more.