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Over 30, Out of Luck

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Less than a month after it issued a warning on the usefulness of PSA screening for prostate cancer, a US government advisory panel says HPV screening may not be very accurate for detecting cervical cancer in women older than 30, reports Bloomberg's Adriel Bettelheim. A draft report from the US Preventive Services Task Force says more evidence is needed to declare HPV screening — usually done by a gynecologist as a test of the cells near the cervix for evidence of the virus — a useful tool for this particular age group, Bettelheim says. The panel will accept public comments on this recommendation until November 16.

The Scan

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.

US Survey Data Suggests Ancestry Testing Leads Way in Awareness, Use of Genetic Testing Awareness

Although roughly three-quarters of surveyed individuals in a Genetics in Medicine study reported awareness of genetic testing, use of such tests was lower and varied with income, ancestry, and disease history.

Coral Genome Leads to Alternative Amino Acid Pathway Found in Other Non-Model Animals

An alternative cysteine biosynthesis pathway unearthed in the Acropora loripes genome subsequently turned up in sequences from non-mammalian, -nematode, or -arthropod animals, researchers report in Science Advances.

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.