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Out With the Ovaries? Not So Fast


Many women undergoing chemotherapy have their ovaries removed and frozen to be able to have children later on, says New Scientist's Catherine de Lange. But new research from Copenhagen University Hospital researcher Elisabeth Larsen and her colleagues suggests that women may be able to skip this procedure and still have children. The team, which presented its research at the European Society for Human Reproduction and Embryology annual meeting in Sweden last week, measured fertility levels in 53 women 10 years after they'd undergone chemotherapy or radiotherapy and found that although they had fewer eggs than women who had never undergone treatment for cancer, the difference wasn't big enough to harm fertility, de Lange says. In a different study, Kristen Tryde Schmidt, also at Copenhagen, found that 35 out of 56 women successfully gave birth after having one ovary removed and frozen prior to cancer treatment, and that 91 percent of them conceived naturally, de Lange adds.

The Scan

UK Pilot Study Suggests Digital Pathway May Expand BRCA Testing in Breast Cancer

A randomized pilot study in the Journal of Medical Genetics points to similar outcomes for breast cancer patients receiving germline BRCA testing through fully digital or partially digital testing pathways.

Survey Sees Genetic Literacy on the Rise, Though Further Education Needed

Survey participants appear to have higher genetic familiarity, knowledge, and skills compared to 2013, though 'room for improvement' remains, an AJHG paper finds.

Study Reveals Molecular, Clinical Features in Colorectal Cancer Cases Involving Multiple Primary Tumors

Researchers compare mismatch repair, microsatellite instability, and tumor mutation burden patterns in synchronous multiple- or single primary colorectal cancers.

FarGen Phase One Sequences Exomes of Nearly 500 From Faroe Islands

The analysis in the European Journal of Human Genetics finds few rare variants and limited geographic structure among Faroese individuals.