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Orion Genomics Teams up with Johns Hopkins Researcher to Develop DNA Methylation-Based Colon Cancer Dx

NEW YORK, June 7 (GenomeWeb News) - Orion Genomics and researchers at the Johns Hopkins University School of Medicine will collaborate to develop a molecular diagnostic test for colon cancer, the company said today.


Under the partnership, Andrew Feinberg, a professor of medicine, molecular biology and genetics, and oncology at Hopkinswill map DNA methylation patterns in cancerous and normal colon tissues using Orion's MethylScope technology.


Orion plans to use the methylation patterns to develop a new type molecular diagnostic test for colon cancer.

The Scan

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.

Study Reviews Family, Provider Responses to Rapid Whole-Genome Sequencing Follow-up

Investigators identified in the European Journal of Human Genetics variable follow-up practices after rapid whole-genome sequencing.

BMI-Related Variants Show Age-Related Stability in UK Biobank Participants

Researchers followed body mass index variant stability with genomic structural equation modeling and genome-wide association studies of 40- to 72-year olds in PLOS Genetics.

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.