Skip to main content
Premium Trial:

Request an Annual Quote

Oooooh, Shiny


When a patient undergoes surgery for cancer, it's important to get every last cell of the tumor out — but cancer cells can be hard to see. To help surgeons see cancer cells more clearly, a team of American and European researchers lit up the cancer cells and made them glow, says Veronique Greenwood at the 80beats blog. In their study published in Nature Medicine, the researchers describe how they tagged ovarian tumor cells with a glowing protein. Many ovarian cancer cells over-express a receptor for folate on their surfaces, and the researchers exploited this by infusing patients with a folate that had a fluorescent tag attached to it, Greenwood says. During surgery, the team shone a laser on the patient's ovaries, which lit up the tagged folate on a nearby computer screen. "This clear marker, they think, made it easier to remove every last bit of the tumors — in eight of their nine patients, the team noticed small tumors they would have missed otherwise," Greenwood adds. The study doesn't address what the long-term results of this surgical technique were, but that question could be addressed by larger, follow-up studies.

The Scan

Support for Moderna Booster

An FDA advisory committee supports authorizing a booster for Moderna's SARS-CoV-2 vaccine, CNN reports.

Testing at UK Lab Suspended

SARS-CoV-2 testing at a UK lab has been suspended following a number of false negative results.

J&J CSO to Step Down

The Wall Street Journal reports that Paul Stoffels will be stepping down as chief scientific officer at Johnson & Johnson by the end of the year.

Science Papers Present Proteo-Genomic Map of Human Health, Brain Tumor Target, Tool to Infer CNVs

In Science this week: gene-protein-disease map, epigenomic and transcriptomic approach highlights potential therapeutic target for gliomas, and more