Skip to main content
Premium Trial:

Request an Annual Quote

Number Crunch Not Enough Information

Premium

Lee Babiss, head of preclinical R&D for Hoffman-LaRoche, told an audience at the Genome Tri-Conference in February that between 1996 and 1999, big pharma doubled the number of targets under scrutiny. But the new flood of targets is not accompanied by a flood of data. Each target is much less documented with literature references than in the past, he says.

Percent of targets in the typical pharmaceutical company’s portfolio that are culled from the scientific literature: 90

Average references in the literature for each target investigated in 1990: 100

Average references per target investigated in 2001: 8

The Scan

Purnell Choppin Dies

Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.

Effectiveness May Decline, Data From Israel Suggests

The New York Times reports that new Israeli data suggests a decline in Pfizer-BioNTech SARS-CoV-2 vaccine effectiveness against Delta variant infection, though protection against severe disease remains high.

To See Future Risk

Slate looks into the use of polygenic risk scores in embryo screening.

PLOS Papers on Methicillin-Resistant Staphylococcus, Bone Marrow Smear Sequencing, More

In PLOS this week: genomic analysis of methicillin-resistant Staphylococcus pseudintermedius, archived bone marrow sequencing, and more.