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Number Crunch The Growth Factor

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The Growth Factor
A look at how the top databases grew last year

December 2001

December 2002
Net Growth
% Growth

GenBank

Release #
127.0
132.0
Base Pairs
15,849,921,438
26,525,934,656
10,676,013,218
67%
Entries
14,976,310
19,808,101
4,831,791

32%

Storage Requirements
58.12 GB
83.35 GB
25.23 GB
43%

Swiss-Prot

Release #
40.0
40.38
Annotated Sequences
101,602
120,607
19,005
19%
Total Amino Acids
37,315,215
44,241,233
6,926,018
19%
References Used
91,880
101,822
9,942
11%

Protein Data Bank

Total Entries
16,972
19,469
2,497
15%
Proteins, Peptides, Viruses
15,200
17,534
2,334
15%
Nucleic Acids
1,041
1,116
75
7%
Protein/Nucleic Acid Complexes
713
801
88
12%
Carbohydrates
18
18
The Scan

Long COVID-19 Susceptibility Clues Contained in Blood Plasma Proteome

A longitudinal study in eBioMedicine found weeks-long blood plasma proteome shifts after SARS-CoV-2 infection, along with proteomic signatures that appeared to coincide with long Covid risk.

Tibetan Study Finds Adaptive Variant Influencing Skin Pigmentation

With a combination of phenotyping and genetic data, researchers document at PNAS a Tibetan-enriched enhancer variant influencing melanin synthesis and ultraviolet light response.

Domestication Linked to Nervous System Genes in Inbred Mouse Strains

Researchers highlighted more than 300 positively selected genes in domesticated mice, including genes linked to nervous system function or behavior in Genome Biology.

ALS Genetic Testing May Be Informative Across Age Ranges, Study Finds

Researchers in the journal Brain identified clinically actionable variants in a significant subset of older ALS patients, prompting them to point to the potential benefits of broader test use.