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NSF Grants in Four Acts


The National Science Foundation received more than $5.6 billion for FY 2006 and is set to receive more than $6 billion next year. Knowing this, we decided to nose through their database to get an inkling of what was spent on a few of our favorite things. The aim of our search was to find top amounts granted to researchers in the realms of proteomics, sequencing, RNAi, and bioinformatics. For each category listed below, we used a range of search terms, then selected a few of the highest awards to show you where the money is going. The list is by no means complete and is meant only to provide an indication of the big-ticket research projects funded by NSF.

California Institute of Technology Collaborative Research in Chemistry: Laboratory for Molecular
$6,000,000 PI: Ahmed Zewail Sciences: Caltech's Multi-Disciplinary Activities
Cornell University From Proplastid to Chloroplast: Understanding Plastid
$3,121,406 PI: Klaas VanWijk Differentiation in Maize through Microarray and Proteome Analysis
Massachusetts Institute of Technology Lanthanide Binding Tags:
$1,600,000 PI: Barbara Imperiali New Chemical Tools for Proteomics
Rensselaer Polytechnic Institute Intein Proteins as Nanoswitches for Biotechnology:
$1,215,191 PI: Georges Belfort Linking Molecular Modeling with Biophysical and Genetic Methods
University of California, Berkeley Collaborative Arabidopsis 2010 Project: Genomics and Proteomics
$1,293,762 PI: Sheng Luan Approaches to the Function of Tyrosine Phosphatases in Arabidopsis
University of California, San Francisco Moderate Resolution Protein Structures by Chemical Cross-linking
$1,957,000 PI: Rodney Guy and Mass Spectrometry
University of Nebraska A Protein Interaction Database For Rice Protein Kinases
$6,057,747 PI: Michael Fromm  
Pennsylvania State University The Floral Genome Project
$7,471,263 PI: Claude dePamphilis  
University of Arizona Oryza Map Alignment Project
$9,081,374 PI: Rod Wing  
University of California, Davis Towards the Complete Gene Inventory and Function of the
$6,828,875 PI: Douglas Cook Medicago Truncatula Genome
University of California, Davis Haplotype Polymorphism in Polyploid Wheats and Their
$5,615,748 PI: Jan Dvorak Diploid Ancestors
University of Minnesota Sequencing the Gene Space of the Model Legume,
$10,911,015 PI: Nevin Young Medicago Truncatula
University of Wisconsin Molecular and Functional Diversity in the Maize Genome
$5,979,015 PI: John Doebley  
Washington University School of Medicine Sequencing the Maize Genome
$12,388,702 PI: Richard Wilson  
Oregon State University Arabidopsis 2010: Function of the Arabidopsis Small RNAs
$1,706,331 PI: James Carrington  
University of Arizona Functional Genomics by Sense-RNAi: A Forward Genetic Approach
$550,048 PI: Richard Jorgensen for Cell-Type-Targeted Mutagenesis and for Polyploids
University of Minnesota Use of Interfering RNAs to Identify Gene Function
$1,018,792 PI: James Gantt in Medicago Truncatula
University of Missouri Gene Silencing Mechanisms in Drosophila
$450,000 PI: James Birchler  
Virginia Polytechnic Institute and State Univ. Computational Models for Gene Silencing: Elucidating a
$1,100,000 PI: Lenwood Heath Pervasive Biological Defensive Response
Carnegie-Mellon University Computational Learning and Discovery in Biological Sequence,
$4,909,988 PI: Raj Reddy Structure, and Function Mapping
Duke University Computational Geometry for Structural Biology and Bioinformatics
$7,228,182 PI: Herbert Edelsbrunner  
University of California, Irvine Developmental Modeling and Informatics
$3,159,425 PI: Eric Mjolsness  
University of California, San Diego Building the Tree of Life: A National Resource for Phyloinformatics
$2,597,000 PI: Francine Berman and Computational Phylogenetics
University of Pennsylvania Mining the Bibliome: Information Extraction from the
$3,232,178 PI: Aravind Joshi Biomedical Literature
University of Texas, Austin Computational Phylogenetics and Applications to Biology
$3,175,735 PI: David Hillis  
Virginia Polytechnic Institute and State Univ. An Integrated Approach to Functional Genomics and Bioinformatics
$3,686,432 PI: Pedro Mendes in a Model Legume



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