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NSF Funds Water Ecology Genetics, Metagenomics at Oklahoma Univ.

NEW YORK (GenomeWeb News) – The National Science Foundation has granted over $1.5 million to the University of Oklahoma to conduct metagenomic and other analyses of suflate-reducing bacteria and research into the genetics and physiology of a water flea as part of ecology studies, the University said Thursday.

University of Oklahoma Research Assistant Professor Amy Callaghan will use a $725,000 grant to study bacteria that use petroleum hydrocarbons as growth substrates. Those studies will involve metagenomics, transcriptomics, and metabolite profiling. The bacteria are involved in anaerobic degradation of alkanes, which are important components of petroleum, and could play a role in the ecological impact of oil spills.

Zoology Professor Lawrence Weider will use a $780,000 grant to study the physiology and genetic structures of Daphnia, a water flea living in lakes. The study will use "resurrection ecology" methods to compare the effects of phosphorus on Daphnia and other aquatic life over a 50-year period.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.