Novartis signaled its continued interest in the proteomics field by penning a biomarker discovery deal with Digilab BioVision, a follow-up to an alliance begun in 2004.
As with the 2004 agreement, the new deal calls for Novartis to use Digilab BioVision’s proprietary Peptidomics technology to evaluate clinical samples for relevant peptides.
“In the first phase of our cooperation, we were successful [in delivering] very satisfying results to our partner and have proved that our Peptidomics approach offers the solution of choice for biomarker discovery,” Digilab BioVision CBO Rainer Voegeli said in a statement announcing the new collaboration.
Hartmut Selle, manager of customer projects for Digilab BioVision, says the new deal “is not a direct continuation [of the 2004 partnership] but it’s related concerning the underlying topic and disease.”
He declined to reveal the specific disease area the two companies will be researching, but signaled that they are looking for biomarkers for the same disease as in the 2004 deal.
“It’s in the same area,” says Selle. “There are some changes in the program, so it’s not just [that] we’re working on the same project. It’s a different one but it’s under the same umbrella, the same topic, the same field of research.” The first agreement, Selle says, was strictly for the discovery of biomarkers. The new agreement “is [for] discovery as well, but if we’re lucky we can add some validation to it.”
For Novartis, the deal is a further sign that it is committed to proteomic research. Last year, for example, scientists at the Genomics Institute of the Novartis Research Foundation developed a new method for selective and reversible capture of modified peptides. Novartis is also part of a partnership, created by the US Food and Drug Administration as part of its Critical Path Initiative, to develop guidelines for biomarker use.
— Tony Fong
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US Patent 7,098,451. Means and method for multiplexing sprays in an electrospray ionization source. Inventor: Melvin Park. Assignee: Bruker Daltonics. Issued: August 29, 2006. The patent relates to a method for “multiplexing a plurality of samples from multiple sprayer devices to be efficiently transferred to a mass analyzer for subsequent analysis,” the abstract states. Sample ions are formed from desolvated sample sprays and then selected for use in a mass analyzer.
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