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Note to Readers: Nov 11, 2014

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Look out next week for a major GenomeWeb redesign that will include a change to our weekly premium newsletters. In Sequence will no longer publish on Tuesdays. Instead, you'll receive the Sequencing Bulletin, one of 10 new weekly topic-specific news mailings that will be available to all GenomeWeb Premium subscribers. You will be able to opt into any of the weekly mailings that you choose, so please visit your My Account page next week to set your email preferences!

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.