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Not so Fast, Leukemia


Investigators at Weill Cornell Medical College and their colleagues at the University of California, San Francisco, have discovered the reason why acute lymphoblastic leukemia cells survive powerful cancer drugs, according to a UCSF press release. As described in the team's study, published in Nature, the researchers found that leukemia cells use a protein called BCL6 to stay alive, and say that targeting the protein may be the key to fighting drug-resistant leukemia. The researchers showed that when mice with drug-resistant leukemia were treated with conventional drugs in combination with a BCL6-supressor — a compound called RI-BPI, developed by Weill Cornell's Ari Melnick — they were cured of the disease, UCSF says.

The Scan

Comfort of Home

The Guardian reports that AstraZeneca is to run more clinical trials from people's homes with the aim of increasing participant diversity.

Keep Under Control

Genetic technologies are among the tools suggested to manage invasive species and feral animals in Australia, Newsweek says.

Just Make It

The New York Times writes that there is increased interest in applying gene synthesis to even more applications.

Nucleic Acids Research Papers on OncoDB, mBodyMap, Genomicus

In Nucleic Acids Research this week: database to analyze large cancer datasets, human body microbe database, and more.