NEW YORK (GenomeWeb News) – After more than a year of on-and-off again negotiations, members of Congress and the White House have failed to reach a compromise agreement to avert the budget sequester penalty, which will slash $85 billion out of federal discretionary spending this fiscal year.

Sequestration takes effect today.

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Robert Redfield is floated as the next director of the US Centers for Disease Control and Prevention, the Washington Post reports.

The New York Times writes that the National Institutes of Health's All of Us Research Program is "ambitious" and that some are concerned it might be overly so.

Representative Lamar Smith's criticism of the National Science Foundation has "changed the nature of the conversation," according to ScienceInsider.

In PLOS this week: non-coding RNA function in yeast, transcriptomic profiles of malaria parasites, and more.