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NINDS to Fund Stroke Genetics Studies

NEW YORK (GenomeWeb News) – The National Institute of Neurological Diseases and Stroke plans to spend $3.6 million over four years to support a study consortium that aims to identify genes or genomic regions that affect either susceptibility to or the outcome of ischemic stroke.

The research may include studies of genetic association with specific sub-phenotypic manifestations of ischemic stroke, such as the age onset, ethnic or population subtype, pathogenic manifestations, variation of severity, brain location, complications, functional recovery, or susceptibility to environmental risk factors.

Other goals of the program are that the SNP genotyping and phenotyping data the project generates end up in a public resource via the Database of Genotype and Phenotype, and that it consists of a collaborative consortium that will work with NINDS.

The funding will support one consortium consisting of multiple Genetic Research Centers and one Data Coordinating Center that are aimed at continuing NINDS's studies of the genetics of ischemic stroke.

Unless the National Institutes of Health grants a special exception, genotyping for the program will be performed at the Center for Inherited Disease Research's genotyping facilities, and the cost of the genotyping will be covered by CIDR.

More information about the NINDS Ischemic Stroke Genetics Consortium grant may be found on NIH's website.

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