Depression patients with variations in two genes — GRIK4 and HTR2A — are more likely to respond to the medication citalopram (Forest’s Celexa) than are people without the variations, a study by the National Institute of Mental Health has found.

“The increased likelihood was small, but when people had both [the GRIK4] variation and one in a different gene [HTR2A] shown to have a similarly small effect in an earlier study, [patients] were 23 percent more likely to respond to citalopram than were people with neither variation,” NIMH says.

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A fire at a Manchester hospital may have destroyed lab equipment and data, the Guardian reports.

Researchers generate a genetic database from skeletal remains from the 1845 Franklin Expedition to the Arctic, Live Science reports.

Researchers in China have begun another trial using CRISPR/Cas9 approaches in cancer patients, according to the Wall Street Journal.

In Science this week: human DNA found in sediments from archeological sites lacking bones, and more.