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NIH Seeks SBIR Grant Proposals to Develop High-throughput Screening Tools; $200K, $400K Grants Available

NEW YORK, Nov. 22 (GenomeWeb News) - The National Institutes of Health is seeking research proposals for projects focused on developing instrumentation to improve the efficiency and boost the capabilities of molecular-library high-throughput-screening systems, according to a program announcement issued last week.


The program looks to fund the development of high-throughput screening instrumentation that "is not only faster and more efficient than currently available systems, but [is] also substantially more sensitive with high levels of specificity, reproducibility, and accuracy," the proposal announcement states.


Examples of potential research areas include novel automated instrumentation for sample maintenance, disbursement, and tracking; innovative methods for highly parallel ligand-/target-binding detection; innovative microfluidics and lab-on-a-chip technologies; and improved cell-based high-content assay formats to acquire many outputs in parallel.


The PA said that the NIH is accepting requests for phase I project budgets of up to $200,000 per year for up to two years, and phase II project budgets of up to $400,000 per year for up to two years. However, the agency said that "no funds have been specifically set aside for this program," and that "the number of awards and the amount of funds provided for awards have not been predetermined."


Eligibility is limited to small business concerns, according to the PA. Individuals capable of carrying out the proposed research are invited to work with their institutions to develop a project application for funding, it adds.


Applications are being accepted on April 1, Aug. 1, and Dec. 1, said the NIH.

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