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NIH Plans to Fund Studies Into Genetic Components of Heart, Lung, Blood Disorders

NEW YORK, Jan. 16 (GenomeWeb News) - The National Institutes of Health will issue a request for applications early this year for genome-wide association studies to identify genetic components related to heart, lung, and blood disorders and their risk factors using existing population, family, and clinical studies, the agency said last week.


The NIH said it will fund genotyping and data-analysis projects focused on developing strategies for genome-wide association studies in existing population, cohort, clinical, and family studies.


"Studies may seek to identify associations of genes with the presence of one particular HLB disorder and may examine interactions among genetic and environmental factors; susceptibility for multiple conditions; or associations of genes with disease risk factors, disease incidence, or therapeutic responsiveness," the NIH said. "A diversity of participant populations regarding age, sex, and race/ethnicity will be supported under this initiative."


The NIH noted that investigators should have access to existing sources of DNA from such population studies, and that it will "fund measurement of genomic data on available samples from existing human studies and analysis of those data." Funding for recruitment, additional phenotyping, or sample acquisition will be provided.