NEW YORK (GenomeWeb News) – Biomedical researchers will now have access to a web-based resource that contains information about proteins that has been produced by the Protein Structural Initiative, the National Institutes of Health said today.
The PSI Structural Genomics Knowledgebase is “an entry point to all of the protein structure and production resources created by the PSI,” which includes structural information on about 2,800 proteins to date.
The SGKB is designed for biologists who are not experts on protein structure, but who “may want to know more about a particular protein related to their research in genetics, biochemistry, pharmacology, bioinformatics, clinical medicine, or other areas,” NIH said.
“Many of these products have always been available, just not all in one place,” explained Jeremy M. Berg, who is director of the National Institute of General Medical Sciences, which is supporting the PSI. “The ability to search the resources developed through the PSI should help a wide range of scientists make use of them to advance their own studies," Berg added.
Researchers will be able to enter the sequence of a protein in a search field on the SGKB’s home page and find the corresponding structure and other similar ones, as well as details about the protein’s function and reports on how the structures were generated. The site will include a glossary of terms and acronyms to help scientists translate the information.
The site also links to information about new technologies and methods, related publications, funding opportunities and outside links. There also will be a link to the PSI Materials Repository, which NIH said is a developing resource that will allow scientists to order PSI-generated clones for use in protein studies.
The PSI SGKB also will have information about how to make proteins, as well as about potential collaborators and recent developments in the field. It also will include enhancements to the site, such as increased searchable databases and editorial and news content about PSI’s ongoing programs.
The PSI SGKB site is located here, and background information about the PSI may be found on the NIGMS website, here.
Further information on the PSI SGKB is also available in the March 7, 2008, issue of GenomeWeb Daily News sister publication BioInform.