NEW YORK (GenomeWeb News) – The National Institutes of Health will use its Small Research Grant program to fund science into rare immunodeficiency diseases, including studies focused on molecular knowledge, biomarkers, and diagnostic technologies.
Funded by the National Institute of Allergy and Infectious Diseases and the National Institute of Child Health and Human Development, this program will give provide up to $50,000 for direct costs per year for each award. The institutes expect to support two new awards each fiscal year.
Primary immunodeficiency diseases are caused by inherited defects in the immune system, and the group includes around 150 diseases and 120 different genes. Although individual primary immunodeficienies are rare, according to NIH, this group as a whole affects one to two percent of the population.
These Small Grants on Primary Immunodeficiency Disorders will fund research that identifies the immunological and molecular characteristics of these diseases, and it will support research seeking to discover and develop improved diagnostic or newborn screening tools.
The studies also could seek to identify and validate biomarkers for these diseases, or aim to understand how a genetic variant can result in immunodeficiency.
Researchers seeking support under this program could propose pilot and feasibility studies, secondary analysis of existing data, and self-contained projects, as well as new research methodologies and technologies. Researchers who have no prior history of receiving independent NIH funding or no NIH funding in immunodeficiency diseases are encouraged to apply for these grants.