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NIH Extends Contract with Galapagos' BioFocus Subsidiary

NEW YORK (GenomeWeb News) – The National Institutes of Health has extended an agreement with Galapagos’ BioFocus DPI service division to continue using the services of the unit for the Molecular Libraries Small Molecule Repository through December 2010, the company said today.
The company said it will receive over $9 million over the course of the two-year extension, which is funded under the NIH Roadmap project.
BioFocus DPI operates the compound management facility for industrial and government customers out of its Compound Focus subsidiary in South San Francisco. The facility has acquired, stored, and distributed compounds for high-throughput biological screening throughout NIH’s US academic network since 2004.
BioFocus DPI sells drug discovery products and services to biotech and pharmaceutical companies, and it provides adenoviral reagents for identifying compound libraries, chemogenomics, and ADMET database products to select targets and compounds.

The Scan

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.

Team Presents Cattle Genotype-Tissue Expression Atlas

Using RNA sequences representing thousands of cattle samples, researchers looked at relationships between cattle genotype and tissue expression in Nature Genetics.

Researchers Map Recombination in Khoe-San Population

With whole-genome sequences for dozens of individuals from the Nama population, researchers saw in Genome Biology fine-scale recombination patterns that clustered outside of other populations.

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.