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NIH Creates Database to Track, Archive Genome-Wide Association Studies

NEW YORK (GenomeWeb News) — The National Library of Medicine yesterday introduced a new database designed to archive and distribute data from genome-wide association studies.
The database, called dbGaP, will include all relevant information about a study, summaries of measured variables, and analysis of statistical association between genes and phenotypes. The National Center for Biotechnology developed the database and will manage it, the NLM said.
The dbGaP will pull data from genotyping arrays that tests for SNPs, and will begin with one National Eye Institute study of age-related macular degeneration and a National Institute of Neurological Disorders and Stroke study of Parkinson’s disease. The NLM said it plans to begin adding to databases for a wide variety of other conditions and illnesses.
NLM Director Donald Lindberg called the project a “milestone in data sharing,” and said it will allow “access to a level of study detail that was not previously available to genotype-phenotype associations.” He said it may also provide “a wealth of hypothesis generating leads.”
NCBI branch Chief James Ostell said the dbGaP “links together the fruits of the world’s recent investment in sequencing the human genome with our decades-long investment in clinical research.”
Additiojnal information about the database can be found here.

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