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NIH Awards in NC

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The Tar Heel State has made a name for itself as a welcoming haven for research, attracting almost $750 million in NIH grant funding this year. The state is home to high-caliber universities and innovative industry (not to mention a striped lighthouse), fostering a fecund environment for genomics and bioinformatics.

To compile the chart below, GT culled NIH’s grants-by-state database to find awards clearly related to disciplines under the systems biology umbrella, and for the sake of space, selected those with the most funding. This list, current as of late August, is not comprehensive.

AWARD

PI PROJECT TITLE

ATTAGENE, INC.

   

$1,481,208

Sergei Makarov Identification of TLR Signaling Network

DUKE UNIVERSITY

   

$2,843,468

Pascal Goldschmidtclermont Comparative Approach to Genomics of Complex Traits
$1,794,134 John York Biological Oscilloscopes Spatio-Temporal Metabolomics

$1,689,075

Elwood Linney Center for Environmental Genomics

$1,000,692

Margaret Pericakvance An Integrated Genomic Approach to Alzheimer’s Disease

$975,766

Robert Cook-Deegan Duke Center for the Study of Public Genomics

$745,377

Howard Rockman Modifier Genes in Heart Failure

$735,034

Elizabeth Hauser GENECARD - Gene Identification in Early Onset CAD

$733,062

R. Rand Allingham Genomic Convergence in Primary Open Angle Glaucoma

$728,625

Joseph Nevins Functional Microarray Facility

$597,842

John York The Role of Inositol Signaling in Human Disease

$529,985

Thomas Mitchell Microfluidic PCR Platform to Detect Microbial DNA

$529,367

Jeffery Vance Genomic Screen To Identify Alzheimer’s Disease Genes

$498,638

Taoshih Hsieh Function and Mechanism of DNA Topoisomerase

$484,382

Arno Greenleaf Phosphorylation and Functions of the RNA Polymerase CTD

$445,115

Paul Modrich Molecular Mechanisms of DNA-Protein Interaction

$299,589

Joseph Nevins Oncogenic Gene Regulatory Networks

NORTH CAROLINA STATE UNIVERSITY

   

$1,303,777

Bruce Weir Statistical and Quantitative Genetics

$434,740

Robert Anholt Comparative Genomics of Glaucoma

UNIVERSITY OF NORTH CAROLINA

   

$1,244,226

T. Kendell Harden G-protein Signal Integration by Multifunctional Proteins
$1,119,290 Darrel Stafford Structure Function & Genetics of Coagulation Factors

$1,000,000

Christoph Borchers Acquisition ¯ Ultra-high Resolution Mass Spectrometer

$958,049

John Ramsey Nanotechnology for the Structural Interrogation of DNA

$911,457

Richard Superfine Computer Integrated Systems for Microscopy & Manipulation

$559,433

Daniel Reed The Carolina Center for Exploratory Genetic Analysis

$544,123

Aziz Sancar DNA Excision Repair and DNA Damage Checkpoints

$495,339

Patrick Sullivan Microarrays & Proteomics in MZ Twins Discordant for CFS

$327,375

Terry Magnuson Allelic Series of Genomic Modifications in ES Cells

$326,659

David Threadgill Functional Genomics of EGFR in Placental Development

$318,639

Jack Griffith DNA-Protein Interactions at the Replication Fork

$306,700

Cynthia Gibas Biophysical Optimization of Oligonucleotide Microarrays

$299,535

Joseph Ibrahim Biostatistics for Research in Genomics and Cancer

$286,089

Rihe Liu Identification of Caspase Substrates from Human Proteome

$281,117

Yi Zhang Histone Methylation in Polycomb Group Gene Silencing

$281,050

Jason Lieb Genomic Approaches to DNA-binding Specificity In Vivo

WAKE FOREST UNIVERSITY HEALTH SCIENCES

   

$753,156

Lynne Wagenknecht Genetics of Adiposity and Glucose Homeostasis

$496,737

Eugene Bleeker Genotype-Phenotype Interactions in Severe Asthma

$494,484

Michele Sale Genetics of African-American Type 2 Diabetes

$491,063

Donald Bowden Mapping Genes for NIDDM Nephropathy in African Americans

The Scan

Genes Linked to White-Tailed Jackrabbits' Winter Coat Color Change

Climate change, the researchers noted in Science, may lead to camouflage mismatch and increase predation of white-tailed jackrabbits.

Adenine Base Editor Targets SCID Mutation in New Study

Researchers from the University of California, Los Angeles, report in Cell that adenine base editing was able to produce functional T lymphocytes in a model of severe combined immune deficiency.

Researchers Find Gene Affecting Alkaline Sensitivity in Plants

Researchers from the Chinese Academy of Science have found a locus affecting alkaline-salinity sensitivity, which could aid in efforts to improve crop productivity, as they report in Science.

International Team Proposes Checklist for Returning Genomic Research Results

Researchers in the European Journal of Human Genetics present a checklist to guide the return of genomic research results to study participants.