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NIH to Award $8M Per Year for High-Throughput Screening Assays

NEW YORK (GenomeWeb News) - The National Institutes of Health will issue approximately $8 million in grants per year between 2008 and 2010 to fund the development of biological assays for high-throughput screening, NIH said Friday in a program announcement.
 
Applicants from public and private spheres may apply for up to $100,000 for direct costs in the first year and up to $25,000 for the second year. NIH said it expects to award around 40 grants per year under the program.
 
The funding, which is being administered by the National Institute of Neurological Disorders and Stroke, has been appropriated for these projects under the NIH’s Molecular Libraries and Imaging Roadmap Initiative.
 
The goal of the program is to develop “novel, scientifically and technologically outstanding assays that can be miniaturized, automated and further used for screening small molecules against structurally diverse libraries such as that maintained by the Molecular Libraries Production Centers Network,” NIH said. Assays developed under the program will be submitted to the MLPCN for screening against a library of more than 200,000 compounds.
 
The screening projects will be aimed at “enabling the design of pharmacological tools to explore cellular and physiological function,” NIH said.
 
The NIH said the researchers under this program will develop assay protocols for “novel molecular targets or phenotypes and transform them into automated screening projects by demonstrating the responsiveness and robustness required for their use in HTS.”
 
This program will be funded twice per year, and there are several dates for letters of intent including Dec. 20, 2007; April 8, 2008; Nov. 6, 2008; March 6, 2009; Nov. 6, 2009; and March 6, 2010.
 
More information about the HTS program can be found here. 

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