Skip to main content
Premium Trial:

Request an Annual Quote

NIGMS Offering $1.6M for Genetics Studies Into 'Complex' Human Phenotypes

NEW YORK (GenomeWeb News) — The National Institute of General Medical Sciences plans to offer $1.6 million to fund three or four new grants to study the genetic mechanisms that underlie complex human phenotypes, and how these different traits are encoded in DNA.
 
The National Institutes of Health said it is asking researchers, including those working in academic, small business, or government labs, to submit proposals for up to $250,000 to be granted over four years.
 
The NIH said the long-term goal of the research is to “understand the molecular mechanisms that underlie complex diseases in humans in order to improve diagnosis, treatment, and prevention.”
 
The research “ideally” would be conducted using human subjects, though the NIH said it expects researchers to develop animal studies.
 
For the purposes of these grants, the NIH said, researchers must plan to demonstrate how the research on animals will inform future experiments concerning complex human phenotypes.
 
Applications are due by Oct. 24.
 
The full RFA may be viewed here.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.