Skip to main content
Premium Trial:

Request an Annual Quote

NIGMS Issues Request for Applications for Systems Biology Research

NEW YORK, Sept. 27 (GenomeWeb News) - The US National Institutes of Health issued an RFA last week requesting systems biology research proposals.


According to the NIH, the National Institute of General Medical Sciences is accepting applications for a program involving the development of "research, training, and outreach programs focused on quantitative, systems level analysis of biological phenomena of biomedical importance within the [institute's] mission."


Under the program, called NIGMS National Centers for Systems Biology, the NIGMS said it plans to support systems biology research in areas that are central to its mission of supporting basic biomedical research and include a focus on developing new computational approaches to biomedical complexity.


Under the program, the NIGMS is committing up to $7 million to fund up to three new grants in response to the RFA. Grant projects may include, but are not limited to, areas such as signaling networks and the regulatory dynamics of cellular processes; supramolecular machines; pattern formation and developmental processes in model systems; and genetic architecture of biological complexity related to inherited variation and environmental fluctuations, said the NIH.


Letters of intent from those seeking grants are due by Jan. 25, 2005. Applications are due by Feb. 25, 2005.


The Scan

Expanded Genetic Testing Uncovers Hereditary Cancer Risk in Significant Subset of Cancer Patients

In Genome Medicine, researchers found pathogenic or likely pathogenic hereditary cancer risk variants in close to 17 percent of the 17,523 patients profiled with expanded germline genetic testing.

Mitochondrial Replacement Therapy Embryos Appear Largely Normal in Single-Cell 'Omics Analyses

Embryos produced with spindle transfer-based mitochondrial replacement had delayed demethylation, but typical aneuploidy and transcriptome features in a PLOS Biology study.

Cancer Patients Report Quality of Life Benefits for Immune Checkpoint Inhibitors

Immune checkpoint inhibitor immunotherapy was linked in JAMA Network Open to enhanced quality of life compared to other treatment types in cancer patients.

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.