Skip to main content
Premium Trial:

Request an Annual Quote

NIGMS Awards VisiGen $100K SBIR for New Biomolecule-Labeling Method

NEW YORK, Sept. 26 (GenomeWeb News) - VisiGen Biotechnologies said today that it has won a Phase 1 Small Business Innovation Research grant from the National Institute of Health's National Institute of General Medical Sciences to develop a new method for labeling DNA, RNA, and proteins.

 

The company did not provide the amount of the grant, but an NIH database lists VisiGen as the recipient of a $100,000 award for a project entitled, "Novel Biolabeling Methods and Reagents."

 

An abstract for the project describes the technology as a "set of novel ATP-fluorescent-dye molecules and ATP-biotin molecules ... for the enzymatic, 5'-end-labeling of an oligonucleotide," and notes that the goal of the Phase I project "is to examine the labeling efficiencies of a library of labeled ATP variants and define the critical threshold for obtaining robust and reproducible signal intensities from labeled-targets hybridized to a microarray."

 

According to the company, the method can be used to directly label RNA for microarray experiments "at a fraction of the cost of current labeling methods" and also has "interesting applications" for the analysis of microRNA.

 

In August, VisiGen was awarded a three-year, $4.2 million grant by the National Human Genome Research Institute as part of its latest round of sequencing technology grants.

The Scan

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.

Team Presents Cattle Genotype-Tissue Expression Atlas

Using RNA sequences representing thousands of cattle samples, researchers looked at relationships between cattle genotype and tissue expression in Nature Genetics.

Researchers Map Recombination in Khoe-San Population

With whole-genome sequences for dozens of individuals from the Nama population, researchers saw in Genome Biology fine-scale recombination patterns that clustered outside of other populations.

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.