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NIGMS Awards GeneGo $750K SBIR Grant to Develop Drug Metabolism, Tox-Prediction Program

NEW YORK, Aug 8 (GenomeWeb News) - GeneGo of St. Joseph, Mich., has received a $750,000 phase II SBIR grant from the National Institute of General Medical Science to further develop its drug metabolism and toxicity prediction tool, MetaDrug, the company said today.

 

The amount of the grant was not immediately known. A call to GeneGo was not returned in time for this publication.

 

GeneGo said it plans to integrate predictive algorithms for ADME/Tox properties into MetaDrug, add a database of ligand-protein interactions from other species than humans, develop in vitro datasets for drug interactions with key human cytochrome P450s, and integrate a novel algorithm for metabolite prediction.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.