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NIEHS to Issue RFP for Protein Biomarker Discovery

NEW YORK, March 14 (GenomeWeb News) - The National Institute of Environmental Health Sciences later this month will solicit requests for proposals from labs that pursue protein biomarker discovery "in subcellular tissue fractions of target tissues or accessible biological fluids such as serum or plasma as a result of toxic insult or disease," according to the Institute.


The Institute also seeks "to achieve mechanistic insights as implicated or demonstrated by changes in proteins as a result of experimental treatments or in studying environmental models of disease."


The Institute has not disclosed the amount of money it has set aside for this RFP.


According to a brief on the FedBizOpps web site, the labs "shall perform proteomic analysis which includes 1) preparation of tissues(s) and serum or plasma; 2) protein analysis; and 3) protein identification.    


"Offerors are encouraged to propose a primary proteomic technology and be capable of using or acquiring additional proteomic platforms (possibly via subcontracts) and to demonstrate the offerors experience with and which substantiate utility of the approach for biological studies for protein expression, identification and characterization of various tissues and of one or more subproteomes," the NIEHS said.    


One award is "anticipated" to be made on Jan. 31, 2006, which will cover a research period of two years with three one-year optional years," the NIEHS said.


The Institute expects to release the RFP on March 22, and proposals will be due May 5.

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