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NIAID Gives TIGR $65M to Sequence Dozens of Pathogenic Organisms

NEW YORK, Oct. 2 (GenomeWeb News) - The Institute for Genomic Research has signed a five-year, $65 million contract with the National Institute of Allergy and Infectious Diseases to sequence and analyze the genomes of "dozens" pathogens and invertebrate vectors of infectious diseases, TIGR said today.

 

TIGR's sister lab, the J. Craig Venter Science Foundation Joint Technology Center, will conduct the sequencing under the contract, while TIGR researchers will lead each project and coordinate the analysis, the institute said.

The Scan

Breast Cancer Risk Related to Pathogenic BRCA1 Mutation May Be Modified by Repeats

Several variable number tandem repeats appear to impact breast cancer risk and age at diagnosis in almost 350 individuals carrying a risky Ashkenazi Jewish BRCA1 founder mutation.

Study Explores Animated Digital Message Approach to Communicate Genetic Test Results to Family Members

In the Journal of Genetic Counseling, the approach showed promise in participants presented with a hypothetical scenario related to a familial hereditary breast and ovarian cancer syndrome diagnosis.

Computational Tool Predicts Mammalian Messenger RNA Degradation Rates

A tool called Saluki, trained with mouse and human messenger RNA data, appears to improve mRNA half-life predictions by taking RNA and genetic features into account, a Genome Biology paper reports.

UK Pilot Study Suggests Digital Pathway May Expand BRCA Testing in Breast Cancer

A randomized pilot study in the Journal of Medical Genetics points to similar outcomes for breast cancer patients receiving germline BRCA testing through fully digital or partially digital testing pathways.