Skip to main content
Premium Trial:

Request an Annual Quote

NIA to Fund Molecular Studies of Circadian Clocks' Roles in Aging

NEW YORK (GenomeWeb News) – The National Institute on Aging plans to spend $1.5 million next year to fund new research aimed at understanding the molecular mechanisms that control circadian clocks in aging tissues.

NIA said this week that it will provide up to $200,000 per year for projects lasting up to five years for research that use 'omics technologies, systems biology, imaging, and single cell studies to find out how molecular and cellular mechanisms influence circadian clocks.

The projects may include studies seeking to understand the impact of alterations in the clock system on gene expression, chromatin remodeling, translation, signaling, and function of individual cells in aging tissues.

The studies also may delve into the pathophysiology of alterations to circadian clock regulation in aged tissues and focus on the response of the clock system to metabolic, nutritional, environmental, and pharmacological challenges.

The research projects may also look into the interaction of epigenetic mechanisms and clock systems during aging, genetic variants involved in the circadian program and their association with aging, and the effects of clock-associated genes during aging.

The Scan

Shape of Them All

According to BBC News, researchers have developed a protein structure database that includes much of the human proteome.

For Flu and More

The Wall Street Journal reports that several vaccine developers are working on mRNA-based vaccines for influenza.

To Boost Women

China's Ministry of Science and Technology aims to boost the number of female researchers through a new policy, reports the South China Morning Post.

Science Papers Describe Approach to Predict Chemotherapeutic Response, Role of Transcriptional Noise

In Science this week: neural network to predict chemotherapeutic response in cancer patients, and more.