Skip to main content
Premium Trial:

Request an Annual Quote

NHGRI to Sequence 18 New Organisms

NEW YORK, Aug. 4 (GenomeWeb News) - The National Human Genome Research Institute today announced that its large-scale sequencing research network will begin sequencing the genomes of 18 new organisms.


The organisms are divided into two groups based on their collective scientific merits, NHGRI said. The first group consists of nine mammals, seven of which will be used primarily to identify conserved sequences among the genomes of humans and other mammals. These seven organisms are: the African savannah elephant (Loxodonta Africana); European common shrew (Sorex araneus); European hedgehog (Erinaceus europeaus); guinea pig (Cavia porcellus); lesser hedgehog tenrec (Echniops telfairi); nine-banded armadillo (Dasypus novemcinctus); and rabbit (Oryctolagus cuniculus).


NHGRI said it would also sequence the domestic cat (Felis catus), to supplement data from the above and because it is an important human disease model, and the orangutan (Pongo pygmaeus), for its importance in understanding basic differences between humans and other primates.


The second group comprises nine non-mammalian organisms: a slime mold (Physarum polycephalum); ciliate (Oxytricha trifallax); choanoflagellate (Monosiga ovata); placozoan (Trichoplax adhaerens); cnidarian (Hydra magnipapillata); snail (Biomphalaria glabrata); two roundworms (Pristionchus pacificu, Trichinella spiralis); and the lamprey (Petromyzon marinus).


The sequencing will be carried out by five centers in the NHGRI-supported large-scale sequencing research network: Agencourt Bioscience; Baylor College of Medicine; the Broad Institute of MIT and Harvard; The Institute for Genomic Research; and the Washington University School of Medicine.

The Scan

Study Follows Consequences of Early Confirmatory Trials for Accelerated Approval Indications

Time to traditional approval or withdrawal was shorter when confirmatory trials started prior to accelerated approval, though overall regulatory outcomes remained similar, a JAMA study finds.

Sequencing Study Leads to Vaccine Target in Bacteria Behind Neonatal Meningitis

Researchers eBioMedicine track down potential vaccine targets with transposon sequencing on mutant bacteria causing neonatal meningitis in mouse models of the disease.

Multiple Myeloma Progression Influenced by Immune Microenvironment Expression

Researchers in NPJ Genomic Medicine compare RNA sequencing profiles of 102,207 individual cells in bone marrow samples from 18 individuals with rapid or non-progressing multiple myeloma.

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.