Skip to main content
Premium Trial:

Request an Annual Quote

NHGRI Releases RFAs for $1,000 Genome

NEW YORK, Feb. 13 (GenomeWeb News) - The National Human Genome Research Institute today released two RFAs aimed at reducing the costs of sequencing a single, full-length mammalian genome to $1,000 - down from current average costs of $10 to $50 million per genome - by the end of a 10-year time frame.


One RFA will commit $6 million in FY2004 and $5 million in FY2005 to fund new or competitive continuation grants for the long-range development of new technologies that could meet the $1,000 goal. The other RFA will commit $8 million in FY2004 and $5 million in FY2005 to fund new or competitive continuation grants for shorter term goals of improving existing technologies to reduce costs by two orders of magnitude below current costs. Respondents to both RFAs can apply under the R21, R33, R01 or P01 granting mechanisms, with deadlines of April 15 and Oct. 15, 2004.


The RFAs gave several potential applications of cost reduction efforts, including: expanding comparative genomic analysis across species, applying human genetic variation studies to individual health care, and analyzing microbial genomes for food and environment monitoring.


The Scan

Latent HIV Found in White Blood Cells of Individuals on Long-Term Treatments

Researchers in Nature Microbiology find HIV genetic material in monocyte white blood cells and in macrophages that differentiated from them in individuals on HIV-suppressive treatment.

Seagull Microbiome Altered by Microplastic Exposure

The overall diversity and the composition at gut microbiome sites appear to coincide with microplastic exposure and ingestion in two wild bird species, according to a new Nature Ecology and Evolution study.

Study Traces Bladder Cancer Risk Contributors in Organ Transplant Recipients

In eLife, genome and transcriptome sequencing reveal mutation signatures, recurrent somatic mutations, and risky virus sequences in bladder cancers occurring in transplant recipients.

Genes Linked to White-Tailed Jackrabbits' Winter Coat Color Change

Climate change, the researchers noted in Science, may lead to camouflage mismatch and increase predation of white-tailed jackrabbits.