Skip to main content
Premium Trial:

Request an Annual Quote

NHGRI to Grant $8.5M for Phenotype, Exposure Measures for Genome-Wide Association Studies

NEW YORK (GenomeWeb News) – The National Human Genome Research Institute will grant $8.5 million for a public health study to identify, develop, and disseminate “readily standardized and implemented phenotypic and environmental exposure measures” to be used with ongoing genome-wide association studies, the National Institutes of Health said last week.
 
The NHGRI said the study should define 15 to 20 high-priority phenotypic and exposure domains such as cancer, pulmonary disease, and others. Investigators should identify standardized measures that are available or are in development; recommend 10 to 15 high priorities for inclusion in genome-wide association studies; and disseminate recommendations to related research communities.
 
The investigator would develop a “basic tool set” to assess phenotypic and environmental exposure that could be applied to ongoing or future genome-wide association studies and other large-scale genomic research.
 
Measurement tools could include assays based on stored biospecimens. The study also could identify measures to be drawn from large-scale prospective gene cohorts or from ongoing biorepositories.
 
Applications for funding must be received by May 17. Additional information can be found here.

The Scan

For Better Odds

Bloomberg reports that a child has been born following polygenic risk score screening as an embryo.

Booster Decision Expected

The New York Times reports the US Food and Drug Administration is expected to authorize a booster dose of the Pfizer-BioNTech SARS-CoV-2 vaccine this week for individuals over 65 or at high risk.

Snipping HIV Out

The Philadelphia Inquirer reports Temple University researchers are to test a gene-editing approach for treating HIV.

PLOS Papers on Cancer Risk Scores, Typhoid Fever in Colombia, Streptococcus Protection

In PLOS this week: application of cancer polygenic risk scores across ancestries, genetic diversity of typhoid fever-causing Salmonella, and more.