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NHGRI Awards Regulome $5.3M for ENCODE Project

NEW YORK, Oct. 10 (GenomeWeb News) -   Regulome, of Seattle, has secured a $5.3 million in funding from the National Human Genome Research Institute, the company said late Thursday. Both grants are part of NHGRI's Encyclopedia of DNA Elements project, also called ENCODE.


Under the project, Regulome will be collaborating with researchers at the University of Washington to apply its technology to the localization and analysis of sequence that regulates gene expression, within a larger region of 30 million base pairs of the genome.


If the pilot phase of the project succeeds, the partners will examine the entire genome, Regulome said.

The Scan

Study Tracks Off-Target Gene Edits Linked to Epigenetic Features

Using machine learning, researchers characterize in BMC Genomics the potential off-target effects of 19 computed or experimentally determined epigenetic features during CRISPR-Cas9 editing.

Coronary Artery Disease Risk Loci, Candidate Genes Identified in GWAS Meta-Analysis

A GWAS in Nature Genetics of nearly 1.4 million coronary artery disease cases and controls focused in on more than 200 candidate causal genes, including the cell motility-related myosin gene MYO9B.

Multiple Sclerosis Contributors Found in Proteome-Wide Association Study

With a combination of genome-wide association and brain proteome data, researchers in the Annals of Clinical and Translational Neurology tracked down dozens of potential multiple sclerosis risk proteins.

Quality Improvement Study Compares Molecular Tumor Boards, Central Consensus Recommendations

With 50 simulated cancer cases, researchers in JAMA Network Open compared molecular tumor board recommendations with central consensus plans at a dozen centers in Japan.