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NHGRI Awards $57M in modENCODE Grants for Drosophila, C. elegans Studies

NEW YORK (GenomeWeb News) - The National Human Genome Research Institute today awarded $57 million in grants to 10 projects under its modENCODE Project, which aims to study the functional elements in the genomes of the model organisms Drosophila melanogaster and Caenorhabditis elegans.
 
The modENCODE funding will be spread over four years, the National Institutes of Health said today. 
 
The effort will build upon the ENCyclopedia Of DNA Elements (ENCODE) project, which NHGRI launched in 2003 with the goal of building a catalog of all elements in the human genome crucial to biological function.
 
“This parallel effort in the fruit fly and worm genomes will provide us with information about the functional landscape of two key model organisms, which should aid our efforts to tackle such questions in humans,” NHGRI director Francis Collins said in a statement.
 
The following is a list of modENCODE grant recipients the NIH named today:
 
Susan Celniker, Lawrence Berkeley National Laboratory
First year, $3.6 million; total funds, $14.5 million
“Comprehensive Characterization of the Drosophila Transcriptome”
 
Steven Henikoff, Fred Hutchinson Cancer Research Center
First-year funds, $429,000; total funds, $7.4 million
“Genome-Wide Profiling of Histone Variants in Drosophila and Caenorhabditis
 
Gary Karpen, Lawrence Berkeley National Laboratory
First -year funds, $1.8 million; total funds, $7.2 million
 “Genome-Wide Mapping of Chromosomal Proteins in Drosophila
 
Eric Lai, Memorial Sloan-Kettering Cancer Center
First-year funds, $470,000; total funds, $1.9 million
 “Annotation of the Small RNA/microRNA Component in the Drosophila Genome“
 
Jason Lieb, The University of North Carolina at Chapel Hill
First-year funds, $1.8 million; total funds, $9.1 million
“Identification of DNA Elements Governing Chromatin Function in C. elegans
 
David MacAlpine, Duke University
First-year funds, $469,000; total funds, $1.9 million
“The Systematic Identification and Analysis of Replication Origins in Drosophila
 
Fabio Piano, New York University.
First-year funds, $397,000; total funds, $1.6 million
“Encyclopedia of C. elegans 3’UTRs and Their Regulatory Elements”
 
Michael Snyder, Yale University
First-year funds, $1.7 million; total funds, $6.6 million
 “Global Identification of Transcription Factor Binding Sites in C. elegans
 
Robert Waterston, University of Washington
 First-year funds, $1.4 million; total funds, $5.4 million
“Global Identification of Transcribed Elements in the C. elegans Genome”
 
Kevin White, University of Chicago
First-year funds, $2.3 million; total funds, $9.1 million
“A Cis Regulatory Map of the Drosophila Genome”

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